Fermentation processes and strains
Processes are matched to strain metabolism for high acid-production and conversion rates. Production strains are developed for amino-acid processes.
Amino-Acid Fermentation
Lysine hydrochloride / sulfate
Lysine products include feed-grade 98 lysine hydrochloride, 70 and 80 lysine grades, and lysine sulfate technology.
98 / 80 / 70Lysine product grades
Product overview
- The clear phase passes through ion exchange, deamination/concentration, acid addition, crystallization, centrifugation and drying to 98 lysine hydrochloride.
- The dense-phase route uses quality control, concentration and granulation drying for 70/80 grades; the ion-exchange side stream separately returns to fermentation preparation.
The amino-acid industry faces intense competition and higher entry barriers, with innovation, new technologies and processes, environmental protection, and energy/emission reduction as development priorities for feed amino acids. Products include 98, 80 and 70 lysine grades, lysine sulfate, threonine and specialty amino acids.
98, 80 and 70 are lysine product grades. The route includes recovery of mother liquor, ammonia water and ion-exchange side streams.
Figures & advantages
Innovative product finishing
Short process routes and reduced investment, targeting high capacity and yield while reducing water, electricity and steam consumption.
DCS automation and quality control
Centralized DCS control integrates processes and automation, reducing manual intervention and labor requirements while supporting stable production and quality control.
Comprehensive technical service
Senior engineers carry out installation, commissioning, production training and management support. Within applicable national standards, the service aims for an improved plant environment, user-friendly operation and achievement of design capacity and performance.
Typical KORN process figures and technical advantages. Final parameters are subject to project design and the technical agreement.
Complete routes & branches
Feed-grade lysine: two product routes
Original bilingual process diagram from the company brochure. All labels and connections are preserved. Translated text outside the diagram is a reading aid.
Process notes and text version
01Strain cultivation and fermentation
- Strain cultivation
- First seed culture
- Second seed culture
- Production fermentation
Supporting inputs: concentrated glucose solution, medium preparation, compressed air and liquid ammonia, and feeding system.
- Filtration
- Clear phase / dense phase
02Feed-grade 98 lysine hydrochloride
- Clear phase
- Ion exchange
- Deamination and concentration
- Hydrochloric acid addition
- Concentration and crystallization
- Centrifugation
Centrifuge mother liquor returns to the hydrochloric acid addition stage.
- Drying
- Feed-grade 98 lysine hydrochloride
03Ammonia-water preparation and recovery
- Liquid NH₃
- Ammonia water
- Ammonia-water preparation
Ammonia water recovered during deamination/concentration returns to preparation.
- Ion exchange
0470 and 80 lysine grades
- Dense phase / fermentation-broth branch
- Quality control
- Concentration
- Granulation drying
- Packaging
- 70 and 80 lysine grades
05Ion-exchange side stream to fermentation
- Ion-exchange wastewater
- Concentration and crystallization
- Centrifugation
- Crystal dissolution
- Fermentation medium preparation
Related technologies
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